Maximizing Your Testosterone- Is Magnesium a Solution?

By Neel Duggal Feb 11, 2015

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To get detailed portrait of the human body’s internal biochemistry, it is helpful to understand how biomarkers impact each other. In this article we investigate recent scientific literature looking at how testosterone levels are affected by a commonly overlooked biomarker: the mineral magnesium. Read below to learn the importance of each biomarker and how monitoring magnesium can boost testosterone and improve muscle growth, sex drive, and overall health and wellness in both men and women.

 

Testosterone is essential for both men and women

When people think of testosterone, they instantly recall it as the “male hormone." Many drugs and fitness articles claim to hold the promise of fixing all of your problems by fixing “low T."

In men, elevated testosterone at puberty helps produce sperm and leads to the formation of secondary sexual characteristics such as body hair. In both men and women, testosterone is important for bone strength, development of lean muscle mass and strength, and maintaining libido and overall mood.

SHBG

In the human body, testosterone is found in the bloodstream in one of two forms. It can be bound to a protein called sex hormone binding globulin – abbreviated as SHBG- or albumin. These proteins transport testosterone throughout the body but it remains biologically inactive (meaning that it does not exert its effects upon the body).

Testosterone can be also be unbound from either protein, in which case it is biologically active and referred to as "free testosterone." Approximately 2-3% of the testosterone in the human body is free [1]. The sum of both of these forms of testosterone is referred to as total testosterone. 

 

Where magnesium comes in

Pumpkin_Seeds

 

Magnesium status is most directly influenced by dietary intake and dietitians recommend consuming a daily dosage of 420 mg for men and 320 mg for women [2]. It is commonly found in foods such as cereal, dark green leafy vegetables, seeds, nuts, cocoa, and seafood [2]. 

Magnesium helps facilitate more than 300 reactions throughout the body [2]. As a result, it is involved in a variety of processes including synthesizing proteins, optimizing muscle and nerve function, regulating blood glucose levels, and controlling blood pressure. However, recent literature shows another previously overlooked benefit: it can increase the amount testosterone in your body. Several recent studies suggest a correlation between magnesium and unbound testosterone- allowing both men and women to maximize its performance-enhancing properties. Below we examine the research illustrating this unusual connection.

 

The magnetic connection- testosterone and magnesium

In a landmark study examining the role of magnesium in total testosterone production, researchers observed the impact of strength development during a 7-week double-blind program.

In it, 12 men received magnesium supplementation while 14 others received placebos and served as the controls. Each subject performed three sets of 10 repetitions of leg press and leg extension three times per week.

As predicted, both groups experienced gains in strength as exhibited by increases muscle mass and performance. However, results indicated a significant increase in testosterone for the group taking magnesium supplementation compared to the control group [3]. These findings suggest that magnesium may play an essential role in testosterone production.

Summary: Magnesium supplementation in conjunction with resistance training increases testosterone production in men

 

Magnesium and athletes – what the science is showing  

In a 2011 study, researchers examined how 4 weeks of magnesium supplementation and exercise affected free and total testosterone levels by creating three groups: one of men taking a 10mg/kg body weight daily magnesium supplement, one that engaged in 90-120 minutes of tae-kwon do five days a week, and one that did both. 

After the four week study, the group that took magnesium supplementation and exercised experienced the greatest increase in testosterone both at rest and after exhaustion [4]. Group 3 had higher testosterone at rest and at exhaustion compared to group 1. These findings led the authors to conclude that magnesium increases total and free testosterone in men, especially for active individuals. [4] 

Summary: In conjunction with low-resistance exercise, magnesium supplementation can increase baseline levels of testosterone more than exercise alone

 

Magnesium and testosterone – lessons from aging research

Elderly

In a large epidemiological study, researchers evaluated the relationship between magnesium and testosterone in 399 elderly men in the Italian region of Tuscany. Instead of the authors providing a dietary magnesium supplementation, they simply monitored existing serum magnesium levels. Researchers found that magnesium was positively associated with total testosterone. [5]

Summary: There is a strong correlation between magnesium and free testosterone in elderly men but the basis of the association is uncertain

 

In conclusion

Testosterone_Optimized

We get it: testosterone is sexy and magnesium isn’t. However, a variety of recent studies show that improving magnesium in your body increases total testosterone. While this is true for men of different age groups, more research needs to be done to examine the effects of magnesium on female subjects as well as the mechanism through which magnesium achieves this increase.

 

Optimize Your Testosterone

 

 

List of References

[1] Emadi-Konjin, Pasha, Jerald Bain, and Irvin L. Bromberg. "Evaluation of an algorithm for calculation of serum “bioavailable” testosterone (BAT)." Clinical biochemistry 36.8 (2003): 591-596.

[2] Maggio, Marcello, et al. "The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men." International journal of endocrinology2014 (2014).

[3] Brilla, Lorraine R., and Timothy F. Haley. "Effect of magnesium supplementation on strength training in humans." Journal of the American College of Nutrition 11.3 (1992): 326-329.

[4] Cinar, Vedat, et al. "Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion." Biological trace element research 140.1 (2011): 18-23.

[5] Maggio, M., et al. "Magnesium and anabolic hormones in older men." International journal of andrology 34.6pt2 (2011): e594-e600.

[6] Maggio, Marcello, et al. "The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men." International journal of endocrinology2014 (2014).

[7] Excoffon, L., et al. "Magnesium effect on testosterone–SHBG association studied by a novel molecular chromatography approach." Journal of pharmaceutical and biomedical analysis 49.2 (2009): 175-180.

 

 

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